10 Best-Rated Psoriasis Creams in 2025
Psoriasis is a chronic skin condition that causes red, scaly patches and discomfort. While there is no cure, topical creams can help manage symptoms like itching, dryness, and inflammation.
1. CeraVe Psoriasis Moisturizing Cream
This dermatologist-recommended cream contains salicylic acid to gently exfoliate flaky skin and ceramides to restore the skin barrier. It’s fragrance-free and non-irritating, making it great for daily use.
2. MG217 Medicated Multi-Symptom Moisturizing Cream
With 3% salicylic acid, this cream helps remove scales and reduce itching. It is enriched with aloe and shea butter for added hydration and soothing relief.
3. Eucerin Intensive Repair Lotion
Designed to address severe dryness and flakiness, this lotion features alpha hydroxy acids for gentle exfoliation and urea to deeply hydrate the skin.
4. Psoriasin Deep Moisturizing Ointment
Formulated with 2% coal tar, this ointment slows down excessive skin cell production, reducing scaling and inflammation. It’s particularly effective for chronic plaque psoriasis.
5. Vanicream Moisturizing Cream
This gentle, dermatologist-tested cream is free from dyes, fragrances, and parabens, making it ideal for people with sensitive skin prone to psoriasis flare-ups.
6. Cortizone 10 Maximum Strength Anti-Itch Creme
A powerful over-the-counter hydrocortisone cream that helps reduce inflammation and itching, providing quick relief during flare-ups.
7. La Roche-Posay Cicaplast Baume B5+
A soothing balm designed to repair the skin barrier and reduce redness and discomfort associated with psoriasis.
8. Kenkoderm Psoriasis Moisturizing Cream
Developed by dermatologists, this fragrance-free cream contains ingredients that help relieve symptoms while keeping the skin moisturized and healthy.
9. E45 Psoriasis Cream
This cream is formulated specifically to reduce scaling, itching, and redness, providing targeted relief for psoriasis symptoms.
10. Bioderma Atoderm Cream
A deeply moisturizing cream that helps restore the skin’s natural barrier, reducing dryness and discomfort associated with psoriasis.