10 Best-Rated Psoriasis Creams in 2025
Psoriasis is a chronic skin condition that causes red, scaly patches and irritation. While there’s no cure, topical creams can help manage symptoms like itching, dryness, and inflammation. The right cream can provide relief by moisturizing the skin, reducing scaling, and soothing discomfort.
1. CeraVe Psoriasis Moisturizing Cream
This dermatologist-recommended formula contains salicylic acid to gently exfoliate flaky skin and ceramides to strengthen the skin barrier. Fragrance-free and non-irritating, it's a great choice for daily care.
2. MG217 Medicated Multi-Symptom Moisturizing Cream
With 3% salicylic acid, this cream helps remove scales while reducing itching. Aloe and shea butter provide deep hydration and soothing relief, making it a top pick for symptom management.
3. Eucerin Intensive Repair Lotion
Designed to combat severe dryness and flakiness, this lotion features alpha hydroxy acids for gentle exfoliation and urea for long-lasting hydration.
4. Psoriasin Deep Moisturizing Ointment
Formulated with 2% coal tar, this ointment slows excessive skin cell production, reducing scaling and inflammation. It’s particularly effective for managing chronic plaque psoriasis.
5. Vanicream Moisturizing Cream
This gentle, dermatologist-tested cream is free from dyes, fragrances, and parabens, making it ideal for sensitive skin prone to psoriasis flare-ups.
6. Cortizone 10 Maximum Strength Anti-Itch Creme
A powerful over-the-counter hydrocortisone cream that quickly relieves itching and inflammation, making it useful during flare-ups.
7. La Roche-Posay Cicaplast Baume B5+
A soothing balm designed to repair the skin barrier and minimize redness and discomfort caused by psoriasis.
8. Kenkoderm Psoriasis Moisturizing Cream
Developed by dermatologists, this fragrance-free cream contains ingredients that help relieve symptoms while keeping the skin moisturized and healthy.
9. E45 Psoriasis Cream
This specialized formula targets scaling, itching, and redness, providing effective relief for psoriasis symptoms.
10. Bioderma Atoderm Cream
A deeply hydrating cream that helps restore the skin’s natural barrier, reducing dryness and discomfort associated with psoriasis.