Many common medications come with a side effect that often flies under the radar: fatigue. Even if you're taking these meds for completely unrelated issues, they might be draining your energy without you knowing it. Let's uncover 10 everyday medications that could be quietly zapping your vitality—and what you can do about it.

1. Antihistamines (for allergies)

Over-the-counter meds like diphenhydramine (Benadryl) are known for causing drowsiness. Even "non-drowsy" options can sometimes slow you down.

2. Blood Pressure Medications

Beta-blockers and some calcium channel blockers can lower your heart rate and make you feel tired or lightheaded.

3. Antidepressants

Certain SSRIs and tricyclic antidepressants, like amitriptyline, are notorious for causing daytime sleepiness, especially early in treatment.

4. Anti-Anxiety Medications

Drugs like diazepam (Valium) and lorazepam (Ativan) calm the nerves—but at a cost. Fatigue and mental fog are common.

5. Pain Relievers (Opioids)

Medications like oxycodone or codeine can dull pain but also significantly slow down your energy levels.

6. Muscle Relaxants

Often prescribed for back pain, these can leave you feeling heavy-limbed and lethargic.

7. Heartburn Medications

Proton pump inhibitors like omeprazole can affect nutrient absorption, leading to fatigue over time.

8. Diuretics

Used to reduce fluid buildup, they can also deplete your body of potassium—a key energy mineral.

9. Antipsychotics

Prescribed for severe mental health conditions, many of these drugs cause sedation as a primary side effect.

10. Sleep Aids

Ironically, some medications taken to help you sleep better at night can make you feel groggy during the day.