Common Medications Linked to Drug-Induced Parkinsonism

Antipsychotic Medications: Used to treat psychiatric conditions like schizophrenia and bipolar disorder, these drugs can block dopamine receptors, leading to parkinsonism symptoms. Examples include haloperidol, risperidone, and chlorpromazine.

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Antemetic Drugs: Medications like metoclopramide and prochlorperazine, prescribed for nausea and gastrointestinal issues, have been associated with parkinsonism due to their dopamine-blocking effects.

Calcium Channel Blockers: Typically used for hypertension, drugs such as flunarizine and cinnarizine have been linked to parkinsonism symptoms.

Antiepileptic Medications: Drugs like valproate and phenytoin, used to manage seizures, may alter neurotransmitter levels, potentially leading to parkinsonism.

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Antidepressants: Certain antidepressants, including selective serotonin reuptake inhibitors (SSRIs) like sertraline, have been reported to cause parkinsonism symptoms in some individuals.

Recognizing Drug-Induced Parkinsonism

Symptoms often mirror those of Parkinson's disease and can include:

Tremors or shaking

Muscle stiffness

Slowed movement (bradykinesia)

Impaired balance and coordination

Notably, drug-induced parkinsonism typically affects both sides of the body equally, whereas Parkinson's disease often starts on one side.

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Managing and Preventing Drug-Induced Parkinsonism

Medication Review: If you experience parkinsonism symptoms, consult your healthcare provider to review your current medications. Adjusting the dosage or switching to an alternative may alleviate symptoms.

Symptom Monitoring: Keep track of any new or worsening symptoms, especially after starting a new medication. Early detection can lead to prompt management.

Lifestyle Adjustments: Engaging in regular physical activity and maintaining a balanced diet can support overall neurological health.